Epithelial-Mesenchymal Transition gene database (dbEMT) Home
dbEMT
Pediatric cancer database
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5728

Name

PTEN

Synonymous

10q23del|BZS|DEC|GLM2|MHAM|MMAC1|PTEN1|TEP1;phosphatase and tensin homolog;PTEN;phosphatase and tensin homolog

Definition

MMAC1 phosphatase and tensin homolog deleted on chromosome 10|mutated in multiple advanced cancers 1|phosphatase and tensin-like protein|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Position

10q23.3

Gene Type

protein-coding

Gene Interactions:

Physical Interaction
Metabolic Interaction
Signaling Interaction

Physical Interaction   [Top]

Interaction Type

Interactor

Data Source

in same component

PDGFBNCI_NATURE;

in same component

PDGFRBNCI_NATURE;

interacts with

AKT1HPRD;

interacts with

ANAPC4INTACT;

interacts with

ANAPC5INTACT;

interacts with

ANAPC7INTACT;

interacts with

ANGBIOGRID;

interacts with

ANGHPRD;

interacts with

ARBIOGRID;

interacts with

ARCELL_MAP;

interacts with

ARHPRD;

interacts with

CAV1BIOGRID;

interacts with

CAV1HPRD;

interacts with

CAV1MINT;

interacts with

CDC27INTACT;

interacts with

CHGBBIOGRID;

interacts with

CHGBHPRD;

interacts with

CHGBMINT;

interacts with

COPS6BIOGRID;

interacts with

COPS6HPRD;

interacts with

COPS6MINT;

interacts with

CSNK2A1BIOGRID;

interacts with

CSNK2A1HPRD;

interacts with

CSNK2A2BIOGRID;

interacts with

CSNK2A2HPRD;

interacts with

DLG1HPRD;

interacts with

ESR1BIOGRID;

interacts with

HBA1BIOGRID;

interacts with

HBA1HPRD;

interacts with

HBA1MINT;

interacts with

MAGI2HPRD;

interacts with

MAGI3BIOGRID;

interacts with

MAGI3HPRD;

interacts with

MAGI3MINT;

interacts with

MAST1HPRD;

interacts with

MAST2HPRD;

interacts with

MAST3HPRD;

interacts with

MVPBIOGRID;

interacts with

MVPHPRD;

interacts with

NEDD4BIOGRID;

interacts with

PDGFRBHPRD;

interacts with

PDGFRBMINT;

interacts with

PPP1CAHPRD;

interacts with

PRDX1MINT;

interacts with

PTK2BIOGRID;

interacts with

PXNBIOGRID;

interacts with

PXNHPRD;

interacts with

SLC9A3R1HPRD;

interacts with

SLC9A3R1MINT;

interacts with

SLC9A3R2HPRD;

interacts with

Slc9a3r2MINT;

interacts with

SLC9A3R2MINT;

interacts with

STK11HPRD;

interacts with

TP53BIOGRID;

interacts with

UBE2IBIOGRID;

interacts with

UBE2IHPRD;

interacts with

UBE2L3BIOGRID;

interacts with

UBE2L3HPRD;

interacts with

UTP14ABIOGRID;

interacts with

UTP14AHPRD;

interacts with

UTP14AMINT;

Metabolic Interaction   [Top]

Interaction Type

Interactor

Data Source

metabolic catalysis

JUNNCI_NATURE;

metabolic catalysis

TP53NCI_NATURE;

sequential catalysis

PTENHUMANCYC;

Signaling Interaction   [Top]

Interaction Type

Interactor

Data Source

reacts with

PDGFBNCI_NATURE;

reacts with

PDGFRBNCI_NATURE;

reacts with

PTENNCI_NATURE;


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